Hydrocortisone Acetate 2.5% / Pramoxine HCl 1% Cream
Generic For: Analpram HC
Medication as Low as $90.00



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- Step 1Choose TreatmentSelect your treatment and quantity.
- Step 2Complete Health QuestionsAnswer a brief medical intake.
- Step 3Provider ReviewA licensed provider reviews your information.
- Step 4Pharmacy ShipsIf approved, your prescription is filled and shipped.
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This cream mixes two helpers. Hydrocortisone calms swelling and itching, and pramoxine numbs the area. It is often used to ease the pain and itch of hemorrhoids.
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15-day supply · $3.00/gram
Refill up to 3 times without a new visit — fast processing.
Price: $90.00
HSA/FSA Eligible+ $30 provider review & $10 shipping only charged if approved
Order Now- Medication$90
- Provider review$30
- Shipping$10
- Total$130
Only charged if approved
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Only charged if a provider approves your prescription
Refill up to 3 times without a new visit — fast processing.
Estimated delivery: Thu–Fri, Oct 22–23 · discreet packaging
- Only charged if a provider approves your prescription
- Estimated delivery: Thu–Fri, Oct 22–23
See price breakdown
How It Works
- Step 1Choose TreatmentSelect your treatment and quantity.
- Step 2Complete Health QuestionsAnswer a brief medical intake.
- Step 3Provider ReviewA licensed provider reviews your information.
- Step 4Pharmacy ShipsIf approved, your prescription is filled and shipped.
Hydrocortisone Acetate / Pramoxine 2.5%/1% Cream
A corticosteroid and topical anesthetic cream for hemorrhoids, anal itching, and inflamed skin conditions
What Hydrocortisone Acetate / Pramoxine 2.5%/1% Cream Treats
What is Hydrocortisone Acetate / Pramoxine 2.5%/1% Cream?
Hydrocortisone acetate 2.5% / pramoxine HCl 1% cream, sold under the brand name Analpram HC, is a prescription topical medication that combines two active ingredients. Hydrocortisone acetate is a corticosteroid that reduces inflammation, redness, and swelling, while pramoxine is a local anesthetic that helps relieve pain, itching, and discomfort. It is commonly prescribed for hemorrhoids and other inflamed or irritated anorectal and skin conditions. This 2 oz cream is applied directly to the affected area as directed by your prescriber.
What it treats
- Hemorrhoids (inflammation and discomfort)
- Anal itching (pruritus ani)
- Inflammatory anorectal conditions
- Corticosteroid-responsive dermatoses
- Itching and irritation of inflamed skin
- Post-procedure anorectal discomfort (as directed by a clinician)
How to Use Hydrocortisone Acetate / Pramoxine 2.5%/1% Cream
- Apply a thin film to the affected area 3 to 4 times daily.
- Use the smallest amount needed for the shortest duration; reassess if no improvement in 2 weeks.
- Do not use occlusive dressings unless directed by your prescriber.
Your prescriber will determine the dose and duration that are right for you. Always follow the directions on your prescription label.
Hydrocortisone Acetate / Pramoxine 2.5%/1% Cream Side Effects
Common side effects
- Burning or stinging at application site
- Itching
- Skin irritation
- Dryness
- Redness
- Folliculitis
- Skin thinning with prolonged use
Serious side effects: get medical help right away
Stop using this medication and seek medical attention right away if you experience:
- Signs of allergic reaction (rash, hives, swelling, difficulty breathing)
- Skin infection at the application site
- Significant skin thinning, striae, or discoloration
- Symptoms of adrenal suppression with prolonged use (fatigue, weakness, weight loss)
- Worsening or spreading irritation
Warnings & Interactions
- For external use only; avoid contact with eyes
- Do not use if allergic to hydrocortisone, pramoxine, or any component
- Prolonged use over large areas may cause systemic corticosteroid absorption
- Not for use on infected skin unless the infection is being treated
- Use in children only under close medical supervision
- Discontinue and contact your prescriber if irritation or sensitization develops
- Tell your prescriber if pregnant or breastfeeding before use
Tell your prescriber about all medications, supplements, and health conditions before starting hydrocortisone acetate / pramoxine 2.5%/1% cream.
Medical Review & Sources
Hydrocortisone Acetate / Pramoxine 2.5%/1% Cream FAQ
What is hydrocortisone acetate 2.5% / pramoxine HCl 1% cream used for?
This combination cream is used to relieve inflammation, itching, and discomfort from hemorrhoids, anal itching, and other inflamed anorectal or skin conditions. Hydrocortisone reduces inflammation while pramoxine numbs the area to ease pain and itching.
How much does hydrocortisone acetate 2.5% / pramoxine 1% cream (2 oz) cost?
The cost of the 2 oz cream varies depending on whether you receive the generic or brand (Analpram HC) and your insurance coverage. The generic version is typically more affordable; our pharmacy team can review pricing options with you before your order ships.
Do I need a prescription for Analpram HC cream?
Yes, hydrocortisone acetate 2.5% / pramoxine 1% cream is a prescription medication in the U.S. A licensed provider must review your health information and issue a valid prescription before our pharmacy can dispense it.
How do I use this cream?
The standard adult dosing is a thin film applied to the affected area 3 to 4 times daily, or as directed by your prescriber. Wash your hands before and after applying, and avoid using it longer than prescribed.
Is the 2.5% strength different from hydrocortisone acetate 2% pramoxine HCl products?
Yes, different products contain different hydrocortisone strengths, and this cream contains hydrocortisone acetate 2.5% with pramoxine HCl 1%. Always confirm the strength on your prescription and use only the product your prescriber ordered.
How does ordering and shipping work?
After your prescription is verified or issued following a provider review, our licensed U.S. pharmacy fills your order and ships it in discreet packaging. Most orders arrive within a few business days, and our pharmacists are available if you have questions.
What side effects should I watch for?
Common side effects include mild burning, stinging, itching, or dryness at the application site. Contact your prescriber if you notice signs of an allergic reaction, skin infection, or significant skin changes such as thinning or discoloration.
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